RNA Details
Disease Name
cardiomegaly
Tissue
heart
RNA Symbol
CIRCYAP
RNA ID
RNA Type
circRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
RT-PCR
Target
ACTG
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
"YAP Circular RNA, circYap, Attenuates Cardiac Fibrosis via Binding with Tropomyosin-4 and Gamma-Actin Decreasing Actin Polymerization"
Year
2021
Function
"Such bindings led to an increased TPM4 interaction with ACTG, resulting in the inhibition of actin polymerization and the following fibrosis."